the-south-asian.com January 2004
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Ashwagandha: Wonder Herb of India
By Dr. Michael Tierra
American Herbal Pharmacopoeia and Therapeutic Compendium, Ashwagandha Root Monograph, coordinated by herbalist Upton, Roy, President of the American Herbalist Guild, et al. 1996 (pending publication).
Arseculeratne, S.N. "Studies on Medicinal Plants of Sri Lanka Part 14: Toxicity of some Traditional Medicinal Herbs" Journal of Ethnopharmacology 13(3):323-35; 1985.
Atal, C.K.; Gupta O.P.; Raghunathan, K.; Dhar, K.L., "Pharmacognosy and Phytochemistry of Withania Somnifera", Central Council for Research in Indian Medicine and Homeopathy, New Delhi, 1975.
Bhatnagar, S.S.et al., eds, The Wealth of India: A Dictionary of Indian Raw Materials and Industrial Products. vol. 10. New Delhi: Publicity and Information Directorate, Council of Social and Industrial Research; 1976:582-585.
Bector, N.P., Puri, A.S., Sharma, D.; "Role of Withania somnifera (Ashwagandha) in various Types of Arthropathies", Indian Journal of Medical Research, 56, 10 October, 1968.
Bhattacharya, S.K et al. "Anti-Stress activity of Sitoindosides VII and VIII, New Acylsteryglucosides from Withania somnifera". Phytotherapy Research 1(1):32-37; 1987.
Kapoor, L.D. CRC Handbook of Ayurvedic Medicinal Plants, Boca Raton, FL:CRC Press, Inc.; 337-8; 1990
Karnick, C.R."A Double-Blind, Placebo-Controlled Clinical Study on the Effects of Withania somnifera and Panax Ginseng Extracts on Psychomotor Performance in Healthy Indian Volunteers." Indian Medicine 3(2,3):1-5; April-July, 1991.
Nadkarani, A.K., Indian Materia Medica, Bombay Popular Prakashan, vol. 1, pp. 1292-94; 1976.
Rao, Prabhu, M.Y., Karahth, K.S., "Neuropharmacological Activity of Withania Somnifera," Fitoterapia, Vol. LXI, No. 3; 1990.
Rahman, A.U., et al., "New Withanolides from Withania spp.," Journal of Natural Products, vol. 56, No. 7, pp. 1000-06; 1993.
Schwarting, A.E., et al., "The Alkaloids of Withania somnifera," Lloydia 26(4):258-73; 1963.
Shibnath, G., et al., "Immunomodulatory and CNS Effects of Sitoindosides IX and X, Two New Glycowithanolides from Withania Somnifera," Phytotherapy Research 3(5); 1989.
Subramanian, S. "Ashwagandha--An Ancient Ayurvedic Drug," Arogya-Journal Health Sciences VIII:135-39; 1982.
Wagner, H. et al. "Plant Adaptogens," Phytomedicine 1(1); 69-70; 1984.
Grandhi, A., "Comparative pharmacological investigation of ashwagandha and ginseng", Journal of Ethnopharmacology (Ireland), 1994: vol. 3, pp 131-135
"inane" because the most valuable herb is always the one that will be the most effective.
Rinpoche, R. Tibetan Medicine, University of California Press; 1976: 14:15)
Frawley, D,; Ayurvedic Healing, Passage Press, 1989: Introduction xv-xvi and Svobada, R.; Lade, A. Tao and Dharma: Chinese Medicine and Ayurveda, Lotus Press, 1995: 80-92.
Dash, V.B., Junius, A.M. M., A Handbook of Ayurveda, Concept Publishing, New Delhi, 1983: 15-25
Sharma, P.V., Introduction to Dravyaguna, i.e. Indian pharmacology; Chaukhambha Orientalia, Varanasi, India, 1976: 38-41)
Bhatnagar et al., 1976 also Schwarting et al., 1963)
Tierra, M., Planetary Herbology, 1988: 3-34; also Frawley, D., Lad, V., The Yoga of Herbs. Santa Fe: Lotus Press; 1986:28-35)
Kuppurajan, K., et al. "Effects of Ashwagandha (Withania Somnifera Dunal) on the Process of Aging in Human Volunteers," Journal of Research in Ayurveda and Saddai: 247-258, 1980
Effect of Glycowithanolides from Withania somnifera on an Animal Model of Alzheimer's Disease and Perturbed Central Cholinergic Markers of Cognition in Rats
Kulkarni, R.R., Treatment of osteoarthritis with a herbomineral formula: double-blind, placebo controlled, cross-over study, Journal of Ethnopharmacology (Ireland) Citation: 33 (1-2 1991):91-95
Upton, R. et. al, American Herbal Pharmacopoeia, 1996 (unpublished to date)
Brekhman, I.I., "Man and Biologically Active Substances", The Effect of Drugs, Diet and
Pollution on Health; Pergamon Press, 1980: 1-89
Badmaev, M.D., Ph.D, Majeed, Muhammed, Ph.D., Ayurvedic Adaptogens and "Bioprotectants", ?
(Bhatnagar, 1976; Ral et al., 1983)
When the entire plant was administered to mice as 25% of the diet, microscopic lesions were found in various organs including the liver and lungs along with vascular congestion and tubular congestion of the kidneys. Considering the widely recognized benefits of taking the herb, and that tonic dosage levels are not really comparable to its experimental administration to animals, it should be considered generally safe, especially when taken with other herbs (arseculaeatne, 1985)
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